Welcome to my home page
Here you will find details of my research interests, publications, CV and how to contact me. I am a research Fellow in Genomics at the Nuffield Department of Medicine in Oxford. Based at the John Radcliffe Hospital, and the Wellcome Trust Centre for Human Genetics, I am a participant in the UKCRC Consortium Modernising Medical Microbiology, a project that aims to harness next-generation sequencing technologies to track and trace clinically important human pathogens. I am also a Principal Investigator at the interdisciplinary Oxford Martin School Institute for Emerging Infections.
My research interests are in the evolution of natural pathogen populations, which I understand through comparative analysis of genomes within and between species. My research activity focuses on the analysis of bacterial pathogen populations, but I also work on viruses and non-pathogenic species. Motivating themes in my work are understanding how transmission, natural selection and recombination shape the diversity of natural populations, and detecting their signature in the genome. Using genomics and disease phenotyping, I am investigating the evolution of bacterial pathogens from the colonization of individual hosts and transmission between hosts, through to the whole-species and phylogenetics levels.